Regina Appiah-Opong profile image

Regina Appiah-Opong

PROFESSOR

Verified email at noguchi.ug.edu.gh Professor of Toxicology, University of Ghana Google Scholar

CollegeCOLLEGE OF HEALTH SCIENCES
School / InstituteNOGUCHI MEM. INST. FOR MED.RES
DepartmentDEPARTMENT OF CLINICAL PATHOLOGY
Toxicology and Pharmacology
Publications

149

Citations

2,736

H-index

28

i10-index

56

Publication activity
Publication statistics
Average citations
18.4
Most cited paper
255
First publication year
1900
Latest publication year
2025
Last updated
14 Sep 2026, 08:58
Publications

149 matching publications

PublicationYearJournalThematic areaCitations
Inhibition of human recombinant cytochrome P450s by curcumin and curcumin decomposition products
R Appiah-Opong, JNM Commandeur, B van Vugt-Lussenburg, ...
2007 Toxicology 235 (1-2), 83-91, 2007 Health Sciences 255
Current perspectives in drug discovery against tuberculosis from natural products
JM Nguta, R Appiah-Opong, AK Nyarko, D Yeboah-Manu, PGA Addo
2015 International Journal of Mycobacteriology 4 (3), 165-183, 2015 Health Sciences 136
Antimycobacterial and cytotoxic activity of selected medicinal plant extracts
JM Nguta, R Appiah-Opong, AK Nyarko, D Yeboah-Manu, PGA Addo, ...
2016 Journal of ethnopharmacology 182, 10-15, 2016 Health Sciences 126
Medicinal plants used to treat TB in Ghana
JM Nguta, R Appiah-Opong, AK Nyarko, D Yeboah-Manu, PGA Addo
2015 International Journal of Mycobacteriology 4 (2), 116-123, 2015 Health Sciences 123
Heavy metals concentration and pollution index (HPI) in drinking water along the southwest coast of Ghana
R Appiah-Opong, A Ofori, M Ofosuhene, E Ofori-Attah, FKE Nunoo, ...
2021 Applied Water Science 11 (3), 57, 2021 Health Sciences 101
Antiplasmodial activity of extracts of Tridax procumbens and Phyllanthus amarus in in vitro Plasmodium falciparum culture systems
R Appiah-Opong, AK Nyarko, D Dodoo, FN Gyang, KA Koram, NK Ayisi
2011 Ghana Medical Journal 45 (4), 143, 2011 Health Sciences 81
HIV-1 proteases from drug-naive West African patients are differentially less susceptible to protease inhibitors
M Kinomoto, R Appiah-Opong, JAM Brandful, M Yokoyama, N Nii-Trebi, ...
2005 Clinical infectious diseases 41 (2), 243-251, 2005 Health Sciences 79
In Vitro Assessment of Anthelmintic Activities of Rauwolfia vomitoria (Apocynaceae) Stem Bark and Roots against Parasitic Stages of Schistosoma mansoni and …
EM Tekwu, KM Bosompem, WK Anyan, R Appiah-Opong, KBA Owusu, ...
2017 Journal of parasitology research 2017 (1), 2583969, 2017 Health Sciences 75
Ethnopharmacological reports on anti-Buruli ulcer medicinal plants in three West African countries
PVT Fokou, AK Nyarko, R Appiah-Opong, LRT Yamthe, P Addo, IK Asante, ...
2015 Journal of ethnopharmacology 172, 297-311, 2015 Health Sciences 74
In vitro antiprotozoan activity and mechanisms of action of selected Ghanaian medicinal plants against Trypanosoma, Leishmania, and Plasmodium parasites
M Ohashi, M Amoa-Bosompem, KD Kwofie, J Agyapong, R Adegle, ...
2018 Phytotherapy Research 32 (8), 1617-1630, 2018 Health Sciences 71
Human breastmilk storage and the glutathione content
NA Ankrah, R Appiah-Opong, C Dzokoto
2000 Journal of tropical pediatrics 46 (2), 111-113, 2000 Health Sciences 70
Structure–activity relationships for the inhibition of recombinant human cytochromes P450 by curcumin analogues
R Appiah-Opong, I de Esch, JNM Commandeur, M Andarini, ...
2008 European journal of medicinal chemistry 43 (8), 1621-1631, 2008 Health Sciences 64
In Vitro Assessment of Antiplasmodial Activity and Cytotoxicity of Polyalthia longifolia Leaf Extracts on Plasmodium falciparum Strain NF54
B Kwansa-Bentum, K Agyeman, J Larbi-Akor, C Anyigba, ...
2019 Malaria research and treatment 2019 (1), 6976298, 2019 Health Sciences 63
Antitrypanosomal activities and mechanisms of action of novel tetracyclic iridoids from Morinda lucida Benth
KD Kwofie, NH Tung, M Suzuki-Ohashi, M Amoa-Bosompem, R Adegle, ...
2016 Antimicrobial agents and chemotherapy 60 (6), 3283-3290, 2016 Health Sciences 63
Toxicity of low levels of methylglyoxal: depletion of blood glutathione and adverse effect on glucose tolerance in mice
NA Ankrah, R Appiah-Opong
1999 Toxicology letters 109 (1-2), 61-67, 1999 Health Sciences 63
Inhibition of human glutathione S-transferases by curcumin and analogues
R Appiah-Opong, JNM Commandeur, E Istyastono, JJ Bogaards, ...
2009 Xenobiotica 39 (4), 302-311, 2009 Health Sciences 62
Application of multi-target phytotherapeutic concept in malaria drug discovery: a systems biology approach in biomarker identification
PA Tarkang, R Appiah-Opong, MF Ofori, LS Ayong, AK Nyarko
2016 Biomarker Research 4 (1), 25, 2016 Health Sciences 58
Interactions between cytochromes P450, glutathione S-transferases and Ghanaian medicinal plants
R Appiah-Opong, JNM Commandeur, C Axson, NPE Vermeulen
2008 Food and Chemical Toxicology 46 (12), 3598-3603, 2008 Health Sciences 57
Ethanolic extract of Nymphaea lotus L. (Nymphaeaceae) leaves exhibits in vitro antioxidant, in vivo anti-inflammatory and cytotoxic activities on Jurkat and MCF-7 …
BB N’guessan, AD Asiamah, NK Arthur, S Frimpong-Manso, P Amoateng, ...
2021 BMC complementary medicine and therapies 21 (1), 22, 2021 Health Sciences 55
Anti-inflammatory activity and mechanism of action of ethanolic leaf extract of Morinda lucida Benth
F Ayertey, E Ofori-Attah, S Antwi, M Amoa-Bosompem, G Djameh, ...
2021 Journal of traditional and complementary medicine 11 (3), 249-258, 2021 Health Sciences 51
Marine algae as source of novel antileishmanial drugs: A review
LR Tchokouaha Yamthe, R Appiah-Opong, PV Tsouh Fokou, N Tsabang, ...
2017 Marine drugs 15 (11), 323, 2017 Health Sciences 47
Plasmodium falciparum: Assessment of Selectivity of Action of Chloroquine, Alchornea cordifolia, Ficus polita, and Other Drugs by a Tetrazolium‐Based …
NK Ayisi, R Appiah-Opong, B Gyan, K Bugyei, F Ekuban
2011 Malaria research and treatment 2011 (1), 816250, 2011 Health Sciences 46
Cytotoxic effects of Albizia zygia (DC) JF Macbr, a Ghanaian medicinal plant, against human T-lymphoblast-like leukemia, prostate and breast cancer cell lines
R Appiah-opong, IK Asante, DO Safo, I Tuffour, E Ofori-attah, T Uto, ...
2016 International Journal of Pharmacy and Pharmaceutical Sciences, 392-396, 2016 Health Sciences 44
New anti-trypanosomal active tetracyclic iridoid isolated from Morinda lucida Benth.
M Suzuki, NH Tung, KD Kwofie, R Adegle, M Amoa-Bosompem, ...
2015 Bioorganic & Medicinal Chemistry Letters 25 (15), 3030-3033, 2015 Health Sciences 43
Antiproliferative, antioxidant activities and apoptosis induction by Morinda lucida and Taraxacum officinale in human HL-60 leukemia cells
R Appiah-Opong, I Tuffour, GK Annor, A Doris, PC Blankson-Darku, ...
2016 Journal of Global Biosciences 5 (7), 4281-4291, 2016 Health Sciences 38