Prof. Samuel kojo Kwofie
PROFESSOR
CollegeCOLLEGE OF BASIC & APPLIED SC.
School / InstituteSCHOOL OF ENGINEERING
DepartmentDEPARTMENT OF BIOMEDICAL ENGINEERING
Artificial IntelligenceBioinformaticsDrug DiscoveryDiagnosticsComputional Bioengineering
Publication activity
Publication statistics
Publications
110 matching publications
| Publication | Year | Journal | Thematic area | Citations |
|---|---|---|---|---|
| Inhibiting Leishmania donovani Sterol Methyltransferase to Identify Lead Compounds Using Molecular Modelling PO Sakyi, SK Kwofie, JK Tuekpe, TM Gwira, E Broni, WA Miller III, ... |
2023 | Pharmaceuticals 16 (3), 330, 2023 | Natural Sciences | 20 |
| Multi-dimensional structural footprint identification for the design of potential scaffolds targeting METTL3 in cancer treatment from natural compounds AR Issahaku, SM Mncube, C Agoni, SK Kwofie, MI Alahmdi, NE Abo-Dya, ... |
2023 | Journal of molecular modeling 29 (4), 122, 2023 | Health Sciences | 20 |
| Homology Modeling, de Novo Design of Ligands, and Molecular Docking Identify Potential Inhibitors of Leishmania donovani 24-Sterol Methyltransferase PO Sakyi, E Broni, RK Amewu, WA Miller III, MD Wilson, SK Kwofie |
2022 | Frontiers in Cellular and Infection Microbiology 12, 859981, 2022 | Natural Sciences | 20 |
| The search for putative hits in combating leishmaniasis: the contributions of natural products over the last decade PO Sakyi, RK Amewu, RNOA Devine, E Ismaila, WA Miller, SK Kwofie |
2021 | Natural products and bioprospecting 11 (5), 489-544, 2021 | Engineering | 20 |
| The emerging paradigm of calcium homeostasis as a new therapeutic target for protozoan parasites Y Gupta, S Goicoechea, CM Pearce, R Mathur, JG Romero, SK Kwofie, ... |
2022 | Medicinal Research Reviews 42 (1), 56-82, 2022 | Health Sciences | 19 |
| Dragon exploratory system on hepatitis C virus (DESHCV) SK Kwofie, A Radovanovic, VS Sundararajan, M Maqungo, A Christoffels, ... |
2011 | Infection, Genetics and Evolution 11 (4), 734-739, 2011 | Health Sciences | 19 |
| Outwitting an old neglected nemesis: a review on leveraging integrated data-driven approaches to aid in unraveling of leishmanicides of therapeutic potential SK Kwofie, E Broni, B Dankwa, KS Enninful, GB Kwarko, L Darko, ... |
2020 | Current Topics in Medicinal Chemistry 20 (5), 349-366, 2020 | Health Sciences | 18 |
| Natural product identification and molecular docking studies of Leishmania major pteridine reductase inhibitors MN Arthur, G Hanson, E Broni, PO Sakyi, H Mensah-Brown, WA Miller III, ... |
2024 | Pharmaceuticals 18 (1), 6, 2024 | Natural Sciences | 16 |
| Design of inhibitors that target the Menin–Mixed-Lineage leukemia interaction MN Arthur, K Bebla, E Broni, C Ashley, M Velazquez, X Hua, ... |
2023 | Computation 12 (1), 3, 2023 | Engineering | 16 |
| Prediction of antischistosomal small molecules using machine learning in the era of big data SK Kwofie, K Agyenkwa-Mawuli, E Broni, WA Miller III, MD Wilson |
2022 | Molecular diversity 26 (3), 1597-1607, 2022 | Engineering | 14 |
| Molecular Informatics Studies of the Iron-Dependent Regulator (ideR) Reveal Potential Novel Anti-Mycobacterium ulcerans Natural Product-Derived Compounds SK Kwofie, KS Enninful, JA Yussif, LA Asante, M Adjei, K Kan-Dapaah, ... |
2019 | Molecules 24 (12), 2299, 2019 | Natural Sciences | 14 |
| Antimalarials: review of Plasmepsins as drug targets and HIV protease inhibitors interactions WA Miller III, J Teye, AO Achieng, RM Mogire, H Akala, JM Ong'echa, ... |
2018 | Current topics in medicinal chemistry 18 (23), 2022-2028, 2018 | Health Sciences | 14 |
| Identification of novel potential inhibitors of varicella-zoster virus thymidine kinase from ethnopharmacologic relevant plants through an in-silico approach SK Kwofie, DG Annan, CA Adinortey, D Boison, GB Kwarko, RA Abban, ... |
2022 | Journal of Biomolecular Structure and Dynamics 40 (23), 12932-12947, 2022 | Health Sciences | 13 |
| In silico discovery of potential inhibitors targeting the RNA binding loop of ADAR2 and 5-HT2CR from traditional chinese natural compounds E Broni, C Ashley, M Velazquez, S Khan, A Striegel, PO Sakyi, S Peracha, ... |
2023 | International Journal of Molecular Sciences 24 (16), 12612, 2023 | Engineering | 12 |
| Whole genome analysis and antimicrobial resistance of Neisseria gonorrhoeae isolates from Ghana B Agbodzi, S Duodu, H Dela, S Kumordjie, C Yeboah, E Behene, ... |
2023 | Frontiers in microbiology 14, 1163450, 2023 | Health Sciences | 12 |
| Molecular docking and dynamics simulations studies of OmpATb identifies four potential novel natural product-derived anti-Mycobacterium tuberculosis compounds SK Kwofie, C Adobor, E Quansah, J Bentil, M Ampadu, WA Miller III, ... |
2020 | Computers in Biology and Medicine 122, 103811, 2020 | Health Sciences | 12 |
| Review of atypical organometallic compounds as antimalarial drugs SK Kwofie, E Broni, B Dankwa, KS Enninful, J Teye, CR Davidson, ... |
2020 | Journal of Chemistry 2020 (1), 9414093, 2020 | Engineering | 12 |
| AICpred: machine Learning-Based prediction of potential Anti-Inflammatory compounds targeting TLR4-MyD88 binding mechanism LN Fry-Nartey, C Akafia, US Nkonu, SB Baiden, IN Dorvi, ... |
2025 | Information 16 (1), 34, 2025 | Engineering | 11 |
| Artificial intelligence and health in Africa: Opportunities, challenges, and ethical considerations MR Ansah, HC Ugo, IA Aboagye, NL Sowah, G Osei, SS Balapangu, ... |
2024 | Examining the rapid advance of digital technology in Africa, 105-125, 2024 | Engineering | 11 |
| Targeting leishmania donovani sterol methyltransferase for leads using pharmacophore modeling and computational molecular mechanics studies PO Sakyi, E Broni, RK Amewu, WA Miller III, MD Wilson, SK Kwofie |
2023 | Informatics in Medicine Unlocked 37, 101162, 2023 | Natural Sciences | 11 |
| Investigating environmental determinants of soil-transmitted helminths transmission using GPS tracking and metagenomics technologies JG Sumboh, K Agyenkwa-Mawuli, E Schwinger, IO Donkor, JEB Akorli, ... |
2023 | medRxiv, 2023 | Engineering | 10 |
| Molecular Modelling and Atomistic Insights into the Binding Mechanism of MmpL3 Mtb SK Kwofie, G Hanson, H Sasu, KS Enninful, FA Mensah, RT Nortey, ... |
2022 | Chemistry & Biodiversity 19 (9), e202200160, 2022 | Natural Sciences | 10 |
| Pharmacophore-Guided Identification of Natural Products as Potential Inhibitors of Mycobacterium ulcerans Cystathionine γ-Synthase MetB SK Kwofie, NNO Dolling, E Donkoh, GM Laryea, L Mosi, WA Miller III, ... |
2021 | Computation 9 (3), 32, 2021 | Engineering | 10 |
| Development of a proteochemometric-based support vector machine model for predicting bioactive molecules of tubulin receptors O Agyapong, WA Miller, MD Wilson, SK Kwofie |
2022 | Molecular Diversity 26 (4), 2231-2242, 2022 | Engineering | 9 |
| In vivo inhibition of gastric acid secretions and H+/K+-ATPase activity, and enhancement of mucin activity by Dissotis rotundifolia plant extract MB Adinortey, C Ansah, J Asiedu-Larbi, SK Kwofie, AS Bockarie, ... |
2022 | Scientific African 17, e01317, 2022 | Engineering | 9 |